Transplantation of human iPS cell-derived glial-rich neural progenitor cells into ALS model mice extends their lifespans Human somatic cells pass through a primitive streak-like stage during reprogramming – Partial elucidation of the reprogramming mechanism – Study of the candidate factors responsible for the DNA demethylation required in iPS cell generation Elucidation of carcinogenic mechanism not involving gene mutation Application of iPS cell technology Method developed for using human iPS cells to create stable and large-scale supply of platelets High-throughput screening (HTS) leads to discovery of compounds that induce efficient differentiation of human iPS cells into nephrogenic cells. Researchers develop method for generation and maintenance culture of human iPS cells suitable for use in cell transplantation Successful replication of FOP pathology using patient-derived iPS cells Method of large-scale erythrocyte production established using erythrocyte progenitor cells with high replication ability Method for identifying low-quality pluripotent stem cells developed using large-scale analysis