A joint group of researchers at Kyoto University, Gladstone Institute and University of California at San Francisco has used iPS cells generated from the cells of patients with FOP (fibrodysplasia ossificans progressiva) to successfully replicate the pathological conditions of the disease. FOP is a disease in which bone gradually forms within muscle, tendon, ligament and other […]
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By transducing two genes (c-MYC and BCL-XL) into iPS cells and ES cells, a Kyoto University research team has succeeded in producing erythrocyte progenitor cells with almost unlimited ability to replicate in vitro, which they then differentiated successfully into mature erythrocytes. Although these erythrocytes consisted mostly of fetal-type hemoglobin, they were confirmed to have oxygen-carrying […]
By transducing two genes (c-MYC and BCL-XL) into iPS cells and ES cells, a Kyoto University research team has succeeded in producing erythrocyte progenitor cells with almost unlimited ability to replicate in vitro, which they then differentiated successfully into mature erythrocytes. Although these erythrocytes consisted mostly of fetal-type hemoglobin, they were confirmed to have oxygen-carrying […]
In a large-scale analysis of human iPS/ES cells, a CiRA research team has discovered the existence of low-quality iPS cell lines which, when induced to differentiate into neurons, leave a residue of undifferentiated cells that cause the formation of teratomas after transplantation into mouse brains. The researchers further established that a characteristic gene was active […]
The Kyoto University Center for iPS cell Research and Application (CiRA) organizes periodic international symposiums, both to promote the worldwide disemination of its research results and to advance iPS cell research. In the 2011 symposium, we plan to hold poster sessions to increase opportunities for discussion among participants.