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  • Dept. of Reprogramming Science
  • Shinya Yamanaka
  • Yasuhiro Yamada
  • Hirohide Saito
  • Knut Woltjen
  • Yoshinori Yoshida
  • Shinji Masui
  • Masato Nakagawa
  • Keisuke Okita
  • Kazutoshi Takahashi
  • Takuya Yamamoto
  • Akitsu Hotta

  

  

  • Dept. of Cell Growth and Differentiation
  • Junya Toguchida
  • Noriyuki Tsumaki
  • Jun K. Yamashita
  • Wataru Fujibuchi
  • Shin Kaneko
  • Kenji Osafune
  • Makoto Ikeya

  

  

  • Dept. of Clinical Application
  • Tatsutoshi Nakahata
  • Jun Takahashi
  • Koji Eto
  • Yoshiya Kawaguchi
  • Haruhisa Inoue
  • Megumu Saito
  • Hidetoshi Sakurai

  

  

  • Dept. of Fundamental Cell Technology
  • Takafumi Kimura
  • Isao Asaka

  

  

  • Uehiro Research Div. for iPS Cell of Ethics
  • Misao Fujita
  • Yoshimi Yashiro

  
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• Research Overview
• Curriculum Vitae
• Publications
• Members

Principal Investigator

Haruhisa Inoue M.D., Ph.D. [ Lab website ]

Research Overview

Molecular-biological analyses are advancing our understanding of intractable neurodegenerative diseases including amyotrophic lateral sclerosis (ALS), but radical care is still to be established. This laboratory aim to perform basic scientific research for further understanding of the disease mechanisms using patient-specific iPS cells, with the perspective of translating the findings into developing methods of treatment and/or prevention of the diseases.

iPS cells derived from ALS (Amyotrophic Lateral Sclerosis) patients

Inclusion body in ALS spinal motor neuron Credit: Dr. Hidefumi Ito, Department of Neurology, Graduate School of Medicine Kyoto University