Research Overview

In cells, molecules spontaneously assemble and form organelles without being enveloped by a lipid membrane, and it has become clear that they play essential roles throughout the cell. Our aim is to elucidate the functions of these non-membranous organelles by focusing on the statistical properties of intracellular molecules, including phase separation.

In particular, we are advancing our research on the principles of cellular reprogramming, which reverse "the cellular clock", using cutting-edge approaches that go beyond traditional molecular biology methods. These approaches include utilizing optogenetics for light manipulation of phase separation and conducting in silico analyses of phase separation through mathematical models. The newfound knowledge will contribute to the development of next-generation iPS cell production technologies.

For more information, please visit our YouTube channel. Additionally, we are recruiting graduate students and postdoctoral researchers. Those interested in our research topics and approaches are warmly welcomed to visit our laboratory.