Research Activities
Research Activities
Publications
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April 24, 2025
Recreating the respiratory tract in a dish: Modeling viral infections and testing treatments
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April 17, 2025
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April 10, 2025
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April 07, 2025
Finding a new drug target to treat Frontotemporal Lobar Degeneration
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April 03, 2025
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February 14, 2025
Safeguarding intestinal stem cells during aging through balanced signaling
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December 04, 2024
Preventing painful BMP-9-mediated flare-ups in fibrodysplasia ossificans progressiva
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December 02, 2024
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November 14, 2024
Enhancing the efficacy of cell transplantation therapy for stroke or traumatic brain injury
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October 25, 2024
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October 21, 2024
Modeling diabetes in minipigs for more accurate testing of potential cell therapies
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October 07, 2024
Preventing skeletal muscle fatigue in Duchenne muscular dystrophy by cell therapy
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October 07, 2024
Scrutinizing cells for clues to a treatment for muscular dystrophy
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October 01, 2024
Unlocking new regenerative pathways in iPS cell-derived epicardium for cardiac repair
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September 30, 2024
Creating a more accurate model of inflammatory bowel disease
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September 06, 2024
Leveraging the power of iPS cell technology to study myeloid neoplasm
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July 12, 2024
Mixing in the flow to build more realistic small intestinal tissues
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June 17, 2024
Refining turbulent flow to scale up iPS cell-based platelet manufacturing
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June 11, 2024
Unraveling the mystery of atherosclerosis in patients with werner syndrome
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June 07, 2024
Suppressing graft-versus-host disease using immunosuppressive iPS cell-derived regulatory T cells
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May 20, 2024
Probing small molecule-RNA interactions by looking through the FOREST
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May 17, 2024
Limiting certain light exposure has the potential to prevent inherited retinal dystrophy
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May 10, 2024
Improving the safety of iPS cell-derived pancreatic islets by eliminating unwanted cells
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May 08, 2024
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May 07, 2024
Designing a novel substrate for myogenic differentiation from iPS cells
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April 24, 2024
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April 16, 2024
Optimizing differentiation protocols and experimental assays to study patient-specific astrocytes
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April 03, 2024
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March 29, 2024
Discovering a new microRNA-regulated pathway to boost iPS cell-derived platelet production
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March 29, 2024
Micro-patterning a new system to induce alveolar and airway epithelial cells
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March 29, 2024
Constructing "on-gel" alveolar organoids as a new screening platform
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March 26, 2024
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March 13, 2024
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March 12, 2024
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March 11, 2024
Inhibition of oxidative phosphorylation points to a new potential treatment for FOP
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February 19, 2024
Combining expertise to characterize the SARS-CoV-2 Omicron XBB.1.5 variant
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January 31, 2024
A comprehensive systematic characterization of the SARS-CoV-2 strain BA.2.86
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January 30, 2024
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January 19, 2024
Constructing a deep generative approach for functional RNA design
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January 18, 2024
Learning from renal development to generate better kidney organoids for regenerative medicine
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January 16, 2024
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December 19, 2023
Shifting energy distribution to treat a rare genetic disorder
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December 06, 2023
Establishing a revolutionary model to study early human embryonic development
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December 01, 2023
Developing more advanced renal organoids to model polycystic kidney disease
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November 17, 2023
Using single-antibodies as a new ingenious tool to build bio-circuitry
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October 17, 2023
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October 17, 2023
Delineating the dynamic transcriptional and epigenetic landscape regulating hematopoiesis
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October 17, 2023
iPSC-derived kidney organoids to model a lifelong renal disease
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October 12, 2023
Capturing the lay public's opinions on genome editing of human embryos
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October 11, 2023
Identification of potential putative drug compounds for treating interstitial lung disease
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October 11, 2023
Optimizing the Tet-On system for homogeneous iPSC myogenic differentiation
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October 04, 2023
Creating an iPS Cell resource for rare and intractable diseases
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August 28, 2023
Exploring new avenues in DMD treatment: CRISPR-Cas3's multi-exon skipping approach
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July 21, 2023
Breaking down molecular barriers to shed light on pattern organization
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July 14, 2023
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June 20, 2023
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June 15, 2023
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June 15, 2023
Generation of high-quality cartilage from iPS cell-derived mesenchymal stem cells
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June 12, 2023
Unveiling the origins of ectopic bones: Insights from neural crest cell research
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May 26, 2023
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April 25, 2023
Creating a rat model for testing cell therapy in Duchenne muscular dystrophy
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April 21, 2023
Establishing the basis for mammalian intracellular computing with mRNA switches
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April 13, 2023
Autophagy-related compound screening for the development of COVID-19 therapeutics
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April 06, 2023
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March 08, 2023
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March 08, 2023
Using organ-on-a-chip technology to elucidate the liver pathophysiology of COVID-19 patients
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March 01, 2023
Selective removal of undifferentiated iPS cells from mesenchymal stem cells
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February 28, 2023
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February 17, 2023
Pathogenesis of skeletal muscle lesions in spinal muscular atrophy
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February 16, 2023
Cyclic RNA switches that regulate gene expression in a cell type-specific manner
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February 03, 2023
Development of a versatile method to synthesize functional mRNAs with diverse 5' cap structures
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January 13, 2023
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January 12, 2023
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January 11, 2023
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December 13, 2022
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November 28, 2022
Phase 1 clinical trial of bosutinib for amyotrophic lateral sclerosis (ALS); iDReAM study
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November 21, 2022
A new sensitive method to detect for minute amounts of contaminating undifferentiated iPS cells
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November 15, 2022
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November 15, 2022
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November 02, 2022
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October 31, 2022
An important host factor in SARS-CoV-2 infection, identified using iPS cell and organoid technology
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September 27, 2022
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September 27, 2022
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September 21, 2022
Japanese regulations on regenerative medicine are failing patients
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June 13, 2022
New method for cell sorting utilizing microRNA switch and magnetic microbeads
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June 02, 2022
COVID-19 research using bronchial organoids and drug discovery applications
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May 30, 2022
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May 20, 2022
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May 16, 2022
Discovery of genes required for survival of human iPS and ES cells
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May 02, 2022
Microwell bag culture for large-scale production of homogeneous islet-like cell clusters
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April 25, 2022
Financial risks posed by unproven cell interventions in Japan
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April 25, 2022
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April 15, 2022
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March 04, 2022
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March 04, 2022
Dissection of the polygenic architecture using iPSC lines derived from Alzheimer's disease
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February 09, 2022
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January 06, 2022
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December 20, 2021
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December 08, 2021
Nanotechnology for genome editing in multiple muscles simultaneously
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December 02, 2021
Stem cells promote recovery regeneration in mice with a rare muscle disease
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November 26, 2021
New potential drugs for muscle dystrophy found using stem cells
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October 28, 2021
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October 27, 2021
The majority of the Japanese public accept embryos made from stem cells for research purposes
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October 21, 2021
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October 15, 2021
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October 01, 2021
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September 17, 2021
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August 31, 2021
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August 31, 2021
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August 24, 2021
iPS cells show therapeutic benefits for a rare muscle dystrophy
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August 23, 2021
Severe COVID-19 symptoms in the elderly are consistent with a weaker immune system
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July 27, 2021
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July 27, 2021
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July 07, 2021
Multiple immune reactions when transplanting cartilage into monkeys
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July 05, 2021
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June 25, 2021
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June 21, 2021
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June 21, 2021
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May 18, 2021
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April 19, 2021
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April 08, 2021
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April 08, 2021
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April 07, 2021
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April 02, 2021
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March 23, 2021
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March 12, 2021
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March 11, 2021
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February 26, 2021
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February 24, 2021
Deep learning amyotrophic lateral sclerosis by taking pictures
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February 16, 2021
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February 10, 2021
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January 29, 2021
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January 18, 2021
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December 25, 2020
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December 22, 2020
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November 18, 2020
The coronavirus pandemic has disrupted scientific publishing
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November 16, 2020
The heat diffusion equation shows its power in drug discovery for brain diseases
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November 13, 2020
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October 30, 2020
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October 30, 2020
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October 16, 2020
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September 16, 2020
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August 26, 2020
Patient stem cells for drug screening a rare autoimmune disease
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August 26, 2020
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August 06, 2020
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August 05, 2020
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July 29, 2020
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July 22, 2020
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July 21, 2020
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July 06, 2020
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July 03, 2020
Harnessing muscle stem cells to fight Duchenne muscular dystrophy
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June 26, 2020
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June 15, 2020
Stem cells pass the final step to an ovary cancer clinical trial
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June 09, 2020
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June 09, 2020
Investigator-initiated clinical trial for familial Alzheimer's disease
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June 08, 2020
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May 15, 2020
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May 11, 2020
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April 10, 2020
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April 09, 2020
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April 07, 2020
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April 02, 2020
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April 02, 2020
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March 30, 2020
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March 13, 2020
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March 11, 2020
A simple synthetic tool to activate translation and build RNA circuits
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March 05, 2020
A new chemical expands kidney cells differentiated from stem cells
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February 28, 2020
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February 26, 2020
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December 27, 2019
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December 17, 2019
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December 06, 2019
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October 24, 2019
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September 24, 2019
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September 12, 2019
Dior and CiRA have started a collaborative research on the mechanism of skin metabolism
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September 11, 2019
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September 04, 2019
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August 29, 2019
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August 22, 2019
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July 22, 2019
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July 02, 2019
In the pancreas, a gene mutation in one cell cause other cells to replicate
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July 02, 2019
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June 28, 2019
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June 21, 2019
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June 11, 2019
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April 09, 2019
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April 09, 2019
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April 03, 2019
Announcement of a clinical trial for amyotrophic lateral sclerosis (ALS)
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March 20, 2019
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March 11, 2019
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March 08, 2019
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February 20, 2019
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February 08, 2019
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January 11, 2019
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November 22, 2018
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November 16, 2018
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November 02, 2018
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October 30, 2018
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October 25, 2018
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September 12, 2018
Genetically-modified cells to lower the cost of blood therapies
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September 12, 2018
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August 29, 2018
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August 29, 2018
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August 29, 2018
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August 28, 2018
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August 27, 2018
Reprogrammed patient cells explain how the environment triggers muscular dystrophy
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August 24, 2018
CiRA scientists reprogram cells to form a key stage in embryonic development
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August 07, 2018
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July 30, 2018
Announcement of physician-initiated clinical trials for Parkinson's disease
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July 13, 2018
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May 25, 2018
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May 25, 2018
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May 04, 2018
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April 26, 2018
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April 13, 2018
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March 05, 2018
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March 05, 2018
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January 29, 2018
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January 11, 2018
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January 09, 2018
Chemical compound A-674563 protects chondrocytes from deterioration
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December 12, 2017
Cheap production of liver cells for disease study and treatment
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December 01, 2017
High throughput drug screening to treat muscular dystrophy patients
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November 24, 2017
iPSC trials and informatics find new drugs for Alzheimer's disease
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November 22, 2017
Gene interactions and positions in the nucleus determine cell identity
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October 23, 2017
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October 18, 2017
Patient stem cells reveal a new drug target in Pompe Disease
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September 28, 2017
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September 19, 2017
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September 01, 2017
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September 01, 2017
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August 31, 2017
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August 31, 2017
Monkeys with Parkinson's disease benefit from human stem cells
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August 09, 2017
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August 09, 2017
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August 01, 2017
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July 27, 2017
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July 21, 2017
Stem cells reveal an early molecular change that initiates a rare neurological disease
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July 11, 2017
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June 05, 2017
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May 25, 2017
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May 22, 2017
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May 19, 2017
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May 19, 2017
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May 19, 2017
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May 03, 2017
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April 04, 2017
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March 30, 2017
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March 16, 2017
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March 16, 2017
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March 16, 2017
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March 07, 2017
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March 02, 2017
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February 15, 2017
The combination of iPS cells and genome editing reveals a molecular cause of neurodegeneration
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February 13, 2017
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February 09, 2017
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February 02, 2017
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January 05, 2017
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December 28, 2016
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November 28, 2016
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November 24, 2016
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November 16, 2016
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November 07, 2016
Unprecedented purity and yield of endothelial cells made in the lab
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November 07, 2016
iPS cell model hints at physiological substances that can promote dopamine production by the brain
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October 28, 2016
Cartilage prepared from iPS cells do not activate immune cells
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October 14, 2016
Japan researchers enhance the purity of cells for Parkinson's disease therapy
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October 11, 2016
Calcium dysregulation contributes to neurodegeneration in cognitive disorders
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October 10, 2016
A new drug compound pushes artificial blood closer to the clinic
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September 26, 2016
New biomaterial enhances the number of differentiated hematopoietic cells from stem cells
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September 09, 2016
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August 09, 2016
Transplantation of non-cardiomyocytes gives best recovery for heart dysfunction
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July 29, 2016
The cell original type does not affect iPS cell differentiation to blood
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July 19, 2016
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July 13, 2016
New iPS cell models to study two distinctive neurodegenerative diseases
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July 13, 2016
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July 01, 2016
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June 17, 2016
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June 15, 2016
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June 06, 2016
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April 29, 2016
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April 19, 2016
Endoderm-lineage organs have distinct progenitors in definitive endoderm
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April 18, 2016
Radiation therapy reduces risk of tumors in stem cell-based neurosurgery
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March 25, 2016
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March 18, 2016
Estradiol promotes integration of iPSC-derived neurons for Parkinson's disease cell therapy
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March 18, 2016
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March 08, 2016
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February 25, 2016
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February 24, 2016
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February 18, 2016
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February 09, 2016
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January 08, 2016
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December 01, 2015
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November 24, 2015
Like building Lego blocks, cell sheets used to treat heart disease
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August 20, 2015
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August 04, 2015
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July 22, 2015
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May 12, 2015
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April 20, 2015
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April 03, 2015
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April 02, 2015
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March 13, 2015
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March 13, 2015
iPS cell-based disease modeling for fibrodysplasia ossificans progressiva
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March 05, 2015
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March 04, 2015
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February 16, 2015
iPS cell-derived pancreatic cells can survive and function in mice
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December 19, 2014
Protocol to induce mesenchymal stem cells with minimal contamination
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November 27, 2014
iPS cells used to correct genetic mutations that cause muscular dystrophy
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November 04, 2014
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August 18, 2014
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August 08, 2014
Human endogenous retroviruses as a key of reprogramming and differentiation potential
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July 02, 2014
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May 13, 2014
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April 24, 2014
Study of the candidate factors responsible for the DNA demethylation required in iPS cell generation
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March 07, 2014
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February 14, 2014
Elucidation of carcinogenic mechanism not involving gene mutation Application of iPS cell technology
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February 14, 2014
Method developed for using human iPS cells to create stable and large-scale supply of platelets
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January 17, 2014
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January 08, 2014
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December 26, 2013
Successful replication of FOP pathology using patient-derived iPS cells
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December 06, 2013
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November 19, 2013
Method for identifying low-quality pluripotent stem cells developed using large-scale analysis
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October 18, 2013
Global Splicing Pattern Reversion during Somatic Cell Reprogramming
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October 17, 2013
Direct induction of chondrogenic cells from human dermal fibroblast culture by defined factors
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September 27, 2013
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September 03, 2013
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August 02, 2013
Modeling of congenital amegakaryocytic thrombocytopenia using iPS cell technology
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July 10, 2013
Highly-efficient method for differentiation of human iPS cells into the immune cells
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April 24, 2013
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April 02, 2013
Transcription Factors Interfering with Dedifferentiation, Promote Differentiation
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February 22, 2013
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January 23, 2013
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January 18, 2013
Three-dimensional design method for protein-responsive RNA switch to regulate cell fate
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January 18, 2013
Scientific paper on generation of paraxial mesodermal cells from iPS cells published in PLOS ONE
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August 01, 2012
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July 17, 2012
PNAS: Donor-dependent variation in hepatic differentiation from human iPS cells
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July 04, 2012
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November 28, 2011
Circulation Research publishes commentary on results of research into immune rejection of iPS cells
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June 14, 2011
Transcription factor Glis1 promotes the generation of safe iPS cells
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May 26, 2011
ECAT11 is expressed in the initial stage of iPS cell induction
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February 28, 2011
The effect of cyclosporin A in causing cardiomyocyte differentiation of iPS cells
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July 27, 2010
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July 07, 2010
Restoration of function in mouse model of spinal injury using safer iPS cells
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July 07, 2010
CiRA reviews potential of iPS cells in cardiovascular medicine
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April 27, 2010
New insights into the molecular control of arterial development
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February 12, 2010
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January 08, 2010
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December 02, 2009
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August 28, 2009
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August 10, 2009
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July 10, 2009
The importance of origins: various iPS cells tested for potential and risk
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October 10, 2008
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July 14, 2008
Assoc. Prof. Yamashita Succeeded in Differentiation of Cardiovascular Cells from Mouse iPS Cells
