Research Activities
Research Activities
Principal Investigators
Dept. of Life Science Frontiers
Risa K. Kawaguchi (Junior Associate Professor)
Publications
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Takizawa N, Kawaguchi RK
- Comprehensive in virio structure probing analysis of the influenza A virus identifies functional RNA structures involved in viral genome replication Computational and Structural Biotechnology Journal, 21:5259-5272 (2023)
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Ballouz S, Kawaguchi RK, Pena MT, Fischer S, Crow M, French L, Knight FM, LB Adams, Gillis J
- The transcriptional legacy of developmental stochasticity Nature Communications, 14:7226 (2023)
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Kawaguchi RK, Kiryu H
- RNA Secondary Structure Alteration Caused by Single Nucleotide Variants Methods in Molecular Biology, 2586:107-120 (2022)
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Kawaguchi RK, Kiryu H
- Genome-Wide RNA Secondary Structure Prediction Methods in Molecular Biology, 2586:35-48 (2022)
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Kawaguchi RK, Tang Z, Fischer S, Rajesh C, Tripathy R, Koo PK, Gillis J.
- Learning single-cell chromatin accessibility profiles using meta-analytic marker genes Briefings in Bioinformatics, 24(1):bbac541 (2022)
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Sheu Y, Kawaguchi RK, Gillis J, Stillman B.
- Prevalent and Dynamic Binding of the Cell Cycle Checkpoint Kinase Rad53 to Gene Promoters eLife, 11:e84320 (2022)
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Kawaguchi RK†, Takahashi M*,†, Miyake M, Kinoshita M, Takahashi S, Ichimura K, Hamamoto R, Narita Y, Sese J.
- Assessing Versatile Machine Learning Models for Glioma Radiogenomic Studies across Hospitals Cancers (Basel), 13(14), 3611 (2021)
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Takahashi S, Takahashi M, Kinoshita M, Miyake M, Kawaguchi R, Shinojima N, Mukasa A, Saito K, Nagane M, Otani R, Higuchi F, Tanaka S, Hata N, Tamura K, Tateishi K, Nishikawa R, Arita H, Nonaka M, Uda T, Fukai J, Okita Y, Tsuyuguchi N, Kanemura Y, Kobayashi K, Sese J, Ichimura K, Narita Y, Hamamoto R.
- Fine-Tuning Approach for Segmentation of Gliomas in Brain Magnetic Resonance Images with a Machine Learning Method to Normalize Image Differences among Facilities Cancers (Basel), 13(6):1415 (2021)
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Miyabayashi K, Baker L, Deschênes A, Traub B, Caligiuri G, Plenker D, Alagesan B, Belleau P, Li S, Kendall J, Jang G, Kawaguchi RK, Somerville T, Tiriac H, Hwang C, Burkhart R, Roberts N, Wood L, Hruban R, Gillis J, Krasnitz A, Vakoc C, Wigler M, Notta F, Gallinger S, Park Y, and Tuveson D.
- Intraductal transplantation models of human pancreatic ductal adenocarcinoma reveal progressive transition of molecular subtypes Cancer Discov, 10(10):1566-89 (2020)
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Kawaguchi R, Kiryu H, Iwakiri J and Sese J.
- reactIDR: evaluation of the statistical reproducibility of high-throughput structural analyses towards a robust RNA structure prediction BMC Bioinformatics, 20 (Suppl 3) :130 (2019). ー Selected for APBC '19 proceedings.
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Kofuji S, Hirayama A, Eberhardt AO, Kawaguchi R, Sugiura Y, Sampetrean O, Ikeda Y, Warren M, Sakamoto N, Kitahara S, Yoshino H, Yamashita D, Sumita K, Wolfe K, Lange L, Ikeda S, Shimada H, Minami N, Malhotra A, Morioka S, Ban Y, Asano M, Flanary VL, Ramkissoon A, Chow LML, Kiyokawa J, Mashimo T, Lucey G, Mareninov S, Ozawa T, Onishi N, Okumura K, Terakawa J, Daikoku T, Wise-Draper T, Majd N, Kofuji K, Sasaki M, Mori M, Kanemura Y, Smith EP, Anastasiou D, Wakimoto H, Holland EC, Yong WH, Horbinski C, Nakano I, DeBerardinis RJ, Bachoo RM, Mischel PS, Yasui W, Suematsu M, Saya H, Soga T, Grummt I, Bierhoff H, Sasaki AT.
- IMP dehydrogenase-2 drives aberrant nucleolar activity and promotes tumorigenesis in glioblastoma Nature Cell Biology, 21:1003-1014 (2019)
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Yoshino H†, Yin G†, Kawaguchi R†, Popov K, Temple B, Sasaki M, Kofuji S, Wolfe K, Kofuji K, Okumura K, Randhawa J, Malhotra A, Majd N, Ikeda Y, Shimada H, Kahoud ER, Haviv S, Iwase S, Asara JM, Campbell SL, and Sasaki AT.
- Identification of lysine methylation in the core RAS GTPase domain by GoMADScan PLOS ONE, 14(8): e0219436 (2019)
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Kawaguchi R and Kiryu H.
- Parallel computation of genome-scale RNA secondary structure to detect structural constraints on human genome BMC Bioinformatics, 17:203 (2016)
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Frith MC and Kawaguchi R.
- Split-alignment of genomes finds orthologies more accurately Genome biology, 16:106 (2015)