Research Activities

Research Activities

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Principal Investigators

Uehiro Research Div. for iPS Cell Ethics  
Misao Fujita (Professor)

Publications

Ikka T, Hatta T, Saito Y, Fujita M.

Does the act on the safety of regenerative medicine in Japan ensure "safety"?: Implications of low adverse event reporting. Stem Cell Reports. 2023.

Sawai T, Hatta T, Akatsuka K, Fujita M.

Human genome editing in clinical applications: Japanese lay and expert attitudes. Frontiers in Genetics. 2023; 14:1205092.

Gyngell C, Munsie M, Fujita M, Thiessen C, Savulescu J, Konstantinov EI.

Ethical analysis of the first porcine cardiac xenotransplantation. Journal of Medical Ethics. 2023

Akatsuka K, Hatta T, Sawai T, Fujita M.

Genome editing of human embryos for research purposes: Japanese lay and expert attitudes. Frontiers in Genetics. 2023; 14:1205067.

Ikka T, Fujita M, Hatta T, Isobe T, Konomi K, Onishi T, Sanada S, Sato Y, Tashiro S, Tobita M.

Difficulties in ensuring review quality performed by committees under the Act on the Safety of Regenerative Medicine in Japan. Stem Cell Reports. 2023; 18(3)613-617.

Urade M, Fujita M, Tsuchiya A, Mori K, Nakazawa E, Takimoto Y, Akabayashi A.

Facts and recommendations regarding when medical institutions report potential abuse to child guidance centers: A cross-sectional study. Pediatric Reports. 2022; 14(4): 479-490.

Murata M, Kawabe K, Hatta T, Maeda S, Fujita M.

Current status of umbilical cord blood storage and provision to private biobanks by institutions handling childbirth in Japan. BMC Medical Ethics. 2022; 23(1).

Fujita M, Hatta T, Ide K.

Current status of cell-based interventions in Japan. Cell Stem Cell. 2022; 29(9): 1294-1297.

Sato H, Fujita M, Tsuchiya A, Hatta T, Mori K, Nakazawa E, Takimoto Y, Akabayashi A.

Disclosing a diagnosis of autism spectrum disorder without intellectual disability to pediatric patients in Japan in early diagnostic stages and associated factors: A cross-sectional study. BioPsychoSocial Medicine. 2022; 16.

Barker RA, Boer GJ, Cattaneo E, Charo RA, Chuva de Sousa Lopes SM, Cong Y, Fujita M, Goldman S, Hermerén G, Hyun I, Lisgo S, Rosser AE, Anthony E, Lindvall O.

The need for a standard for informed consent for collection of human fetal material. Stem Cell Reports. 2022; 17(6): 1245-1247.

Hatta T, Ide K, Fujita M, Ikka T.

Financial risks posed by unproven stem cell interventions: Estimation of refunds from medical expense deductions in Japan. Stem Cell Reports, 2022.

Sawai T, Hatta T, Akatsuka K, Fujita M.

Public attitudes in Japan toward the creation and use of gametes derived from human-induced pluripotent stem cells. Future Science OA, 2021.

Akatsuka K, Hatta T, Sawai T, Fujita M.

Public attitudes in Japan toward the reproductive use of gametes derived from human-induced pluripotent stem cells. Future Science OA, 2021.

Lovell-Badge R, Anthony E, Barker RA, Bubela T, Brivanlou AH, Carpenter M, Charo RA, Clark A, Clayton E, Cong Y, Daley GQ, Fu J, Fujita M, Greenfield A, Goldman SA, Hill L, Hyun I, Isasi R, Kahn J, Kato K, Kim J-S, Kimmelman J, Knoblich JA, Mathews D, Montserrat N, Mosher J, Munsie M, Nakauchi H, Naldini L, Naughton G, Niakan K, Ogbogu U, Pedersen R, Rivron N, Rooke H, Rossant J, Round J, Saitou M, Sipp D, Steffann J, Sugarman J, Surani A, Takahashi J, Tang F, Turner L, Zettler PJ, Zhai X.

ISSCR guidelines for stem cell research and clinical translation: The 2021 update. Stem Cell Reports. 2021.

Hyun I, Clayton EW, Cong Y, Fujita M, Goldman SA, Hill LR, Monserrat N, Nakauchi H, Pedersen RA, Rooke HM, Takahashi J, Knoblich JA.

ISSCR guidelines for the transfer of human pluripotent stem cells and their direct derivatives into animal hosts. Stem Cell Reports. 2021.

Ide K, Matsuoka N, Fujita M.

Ethical aspects of brain organoid research in news reports: An exploratory descriptive analysis. Medicina. 2021; 57(6):532.

Ide K, Koshiba H, Hawke P, Fujita M.

Guidelines are urgently needed for the use of preprints as a source of information. J Epidemiol. 2021; 31(1). 97-99.

Crane AT, Shen FX, Brown JL, Cormack W, Ruiz-Estevez M, Voth JP, Sawai T, Hatta T, Fujita M, Low WC.

The American public is ready to accept human-animal chimera research Stem Cell Reports. 2020; 15(4): 904-810.

Sawai T, Minakawa T, Pugh J, Akatsuka K, Yamashita JK, Fujita M.

The moral status of human embryo‐like structures: Potentiality matters? EMBO Reports. 2020; 20(8): 32-36.

Sawai T, Sakaguchi H, Thomas E, Takahashi J, Fujita M.

The ethics of cerebral organoid research: Being conscious of consciousness. Stem Cell Reports. 2019; 13(1):470-477

Ozeki-Hayashi R, Fujita M, Tsuchiya A, Hatta T, Nakazawa E, Takimoto Y, Akabayashi A.

Beliefs held by breast surgeons that impact the treatment decision process for advanced breast cancer patients: A qualitative study. Breast Cancer: Targets and Therapy. 2019; 11: 221-229.

Sawai T, Hatta T, Fujita M.

Japan significantly relaxes its human-animal chimeric embryo research regulations. Cell Stem Cell. 2019; 24 (4): 513-51.

Fujita M, Tabuchi K.

A rebuttal to Akabayashi and colleagues' criticisms of the iPSC stock project. Journal of Medical Ethics. 2019; 45(7):476-477.

Sawai T, Hatta T, Fujita M.

The Japanese generally accept human-animal chimeric embryo research but are concerned about human cells contributing to brain and gametes. Stem Cells Translational Medicine. 2017; 6(8): 1749-1750.

Sawai T, Hatta T, Fujita M.

Public attitudes in Japan towards human-animal chimeric embryo research using human induced pluripotent stem cells. Regenerative Medicine. 2017;12(3):233-248.

Takashima K, Takimoto Y, Nakazawa E, Hayashi Y, Tsuchiya A, Fujita M, Akabayashi A.

Discovery and informing study participants of incidental findings detected in brain magnetic resonance imaging studies: Review and multi-institutional study. Brain and Behavior. 2017;7(5):e00676.

Sawai T, Fujita M.

The problem of dual use in relation to decoded neurofeedback. AJOB Neuroscience. 2016; 7(4): 253-254.

Fujita M, Hatta T, Reina O, Akabayashi A.

The current status of clinics providing private practice cell therapy in Japan. Regenerative Medicine 2016;11(1):23-32.

Takahashi S, Fujita M, Akabayashi A.

"Mottainai" embryos and the earthquake. J Clin Res Bioeth. 2015;7:258

Ikka T, Fujita M, Yashiro Y, Ikegaya H.

Recent court ruling in Japan exemplifies another layer of regulation for regenerative therapy. Cell Stem Cell 2015; 17(5): 507-508.

Fujita M, Hatta T, Sawai T, Takahashi J.

Risk of tumorigenesis and patient hope. AJOB Neuroscience 2015; 6: 69-70.

Fujita M, Hayashi Y, Tashiro S, Takashima K, Nakazawa E, Akabayashi A.

Handling incidental findings in neuroimaging research in Japan: Current state of research facilities and attitudes of investigators and the general population. Health Research Policy and Systems 2014; 12: 58.

Fujita M, Yashiro Y, Suzuki M.

Throwing the baby out with the bathwater: A critique of Sparrow's inclusive definition of the term 'in vitro eugenics.' J Med Ethics. 2013 Aug 28.

Takahashi S, Fujita M, Fujimoto A, Fujiwara T, Yano T, Tsutsumi O, Taketani Y, Akabayashi A.

The decision-making process for the fate of frozen embryos by Japanese infertile women: A qualitative study. BMC Medical Ethics 2012; 13: 9.

Fujita M, Matsui K, Monden M, Akabayashi A.

Attitudes of medical professionals and transplant facilities toward living donor liver transplantation in Japan. Transplantation Proceedings 2010; 42: 1453-9.

Fujita M, Slingsby BT, Akabayashi A.

Transplant tourism from Japan. American Journal of Bioethics 2010; 10(2): 24-6.
Books

Akabayashi A, Fujita M.

The present and future of stem cell therapy in Japan. In: Uehiro T (ed). Ethics for the Future of Life, 9-19. Oxford Uehiro Center for Practical Ethics; 2013.
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