研究活動
Research Activities
研究活動
Research Activities
主任研究者
Principal Investigators
臨床応用研究部門 後藤 慎平 教授
発表論文
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Muramoto Y, Takahashi S, Halfmann PJ, Gotoh S, Noda T, Kawaoka Y
- Omicron variants BA.5 and BQ.1.1 lack efficient replicative capacity at elevated temperatures. Lancet Microbe., 2023 Apr 24;S2666-5247(23)00100-3.
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Xu Y, Feng G, Yano T, Masuda S, Nagao M, Gotoh S, Ikejiri M, Tanabe M, Takeuchi K
- Characteristic genetic spectrum of primary ciliary dyskinesia in Japanese patients and global ethnic heterogeneity: population-based genomic variation database analysis. J Hum Gen., 2023 Mar 2. doi: 10.1038/s10038-023-01142-4.
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Tamai K, Sakai K, Yamaki H, Moriguchi K, Igura K, Maehana S, Suezawa T, Takehara K, Hagiwara M, Hirai T, Gotoh S
- iPS cell-derived mesenchymal cells that support alveolar organoid development. Cell Rep Methods., 2022 Sep 19;2(10):100314.
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Masui A, Hirai T, Gotoh S
- Perspectives of future lung toxicology studies using human pluripotent stem cells. Archives of Toxicology, 2022 Feb; 96(2):389-402. Review
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Suezawa T, Kanagaki S, Moriguchi K, Masui A, Nakao K, Toyomoto M, Tamai K, Mikawa R, Hirai T, Murakami K, Hagiwara M, Gotoh S.
- Disease modeling of pulmonary fibrosis using human pluripotent stem cell-derived alveolar organoids. Stem Cell Reports, 2021 Dec 14;16(12):2973-2987.
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Suezawa T, Kanagaki S, Korogi Y, Nakao K, Hirai T, Murakami K, Hagiwara M, Gotoh S.
- Modeling of lung phenotype of Hermansky-Pudlak syndrome type I using patient-specific iPSCs. Respiratory Research, 2021 Nov 4;22(1):284.
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Ikeo S, Yamamoto Y, Ikeda K, Sone N, Korogi Y, Tomiyama L, Matsumoto H, Hirai T, Hagiwara M,
Gotoh S. - Core-shell hydrogel microfiber-expanded pluripotent stem cell-derived lung progenitors applicable to lung reconstruction in vivo. Biomaterials, 2021 Sep; 276:121031.
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Sone N, Konishi S, Igura K, Tamai K, Ikeo S, Korogi Y, Kanagaki S, Namba T, Yamamoto Y, Xu Y, Takeuchi K, Adachi Y, Chen-Yoshikawa TF, Date H, Hagiwara M, Tsukita S, Hirai T, Torisawa Y, Gotoh S.
- Multicellular modeling of ciliopathy by combining iPS cells and microfluidic airway-on-a-chip technology. Science Translational Medicine, 2021 Jul 7; 13(601): eabb1298.
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Kanagaki S, Suezawa T, Moriguchi K, Nakao K, Toyomoto M, Murakami K, Hagiwara M, Gotoh S.
- Hydroxypropyl cyclodextrin improves amiodarone-induced aberrant lipid homeostasis of alveolar cells. American Journal of Respiratory Cell and Molecular Biology, 2021 Apr; 64(4): 504-514.
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Kanagaki S, Ikeo S, Suezawa T, Yamamoto Y, Seki M, Hirai T, Hagiwara M, Suzuki Y, Gotoh S.
- Directed induction of alveolar type I cells derived from pluripotent stem cells via Wnt signaling inhibition. Stem Cells, 2020 Feb; 39(2): 156-169.
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Korogi Y, Gotoh S, Ikeo S, Yamamoto Y, Sone N, Tamai K, Konishi S, Nagasaki T, Matsumoto H, Ito I, Chen-Yoshikawa TF, Date H, Hagiwara M, Asaka I, Hotta A, Mishima M, Hirai T.
- In vitro disease modeling of Hermansky-Pudlak Syndrome type 2 using human induced pluripotent stem cell-derived alveolar organoids. Stem Cell Reports, 2019 Mar 5; 12: 431-440.
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Yamamoto Y, Gotoh S, Korogi Y, Seki M, Konishi S, Ikeo S, Sone N, Nagasaki T, Matsumoto H, Muro S, Ito I, Hirai T, Kohno T, Suzuki Y, Mishima M.
- Long-term expansion of alveolar stem cells derived from human iPS cells in organoids. Nature Methods, 2017 Nov; 14(11):1097-1106.
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Konishi S, Gotoh S, Tateishi K, Yamamoto Y, Korogi Y, Nagasaki T, Matsumoto H, Muro S, Hirai T, Ito I, Tsukita S, Mishima M.
- Directed induction of functional multi-ciliated cells in proximal airway epithelial spheroids from human pluripotent stem cells. Stem Cell Reports, 2016 Jan; 6(1): 18-25.
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Gotoh S, Ito I, Nagasaki T, Yamamoto Y, Konishi S, Korogi Y, Matsumoto H, Muro S, Hirai T, Funato M, Mae S, Toyoda T, Sato-Otsubo A, Ogawa S, Osafune K, Mishima M.
- Generation of alveolar epithelial spheroids via isolated progenitor cells from human pluripotent stem cells. Stem Cell Reports, 2014 Sep 9; 3(3): 394-403.