研究活動
Research Activities

研究活動
Research Activities

Home › 研究活動 › 主任研究者 › 吉田 善紀 准教授

主任研究者
Principal Investigators

増殖分化機構研究部門 吉田 善紀 准教授

発表論文

Gao J, Makiyama T, Yamamoto Y, Kobayashi T, Aoki H, Maurissen TL, Wuriyanghai Y, Kashiwa A, Imamura T, Aizawa T, Huang H, Kohjitani H, Nishikawa M, Chonabayashi K, Fukuyama M, Manabe H, Nakau K, Wada T, Kato K, Toyoda F, Yoshida Y, Makita N, Woltjen K, Ohno S, Kurebayashi N, Murayama T, Sakurai T, Horie M, Kimura T.

Novel Calmodulin Variant p.E46K Associated With Severe Catecholaminergic Polymorphic Ventricular Tachycardia Produces Robust Arrhythmogenicity in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes. Circ Arrhythm Electrophysiol, 2023 Mar 3:e011387.

Tian Y, Tsujisaka Y, Li VY, Tani K, Lucena-Cacace A, Yoshida Y.

Immunosuppressants Tacrolimus and Sirolimus revert the cardiac antifibrotic properties of p38-MAPK inhibition in 3D-multicellular human iPSC-heart organoids. Front Cell Dev Biol. 2022 Nov 11;10:1001453.

Katagiri T, Espinoza JL, Uemori M, Ikeda H, Hosokawa K, Ishiyama K, Yoroidaka T, Imi T, Takamatsu H, Ozawa T, Kishi H, Yamamoto Y, Elbadry MI, Yoshida Y, Chonabayashi K, Takenaka K, Akashi K, Nannya Y, Ogawa S, Nakao S.

Hematopoietic stem progenitor cells with malignancy-related gene mutations in patients with acquired aplastic anemia are characterized by the increased expression of CXCR4 EJHaem. 2022 Jul 3;3(3):669-680.

Kashiwa A, Makiyama T, Kohjitani H, Maurissen TL, Ishikawa T, Yamamoto Y, Wuriyanghai Y, Gao J, Huang H, Imamura T, Aizawa T, Nishikawa M, Chonabayashi K, Mishima H, Ohno S, Toyoda F, Sato S, Yoshiura KI, Takahashi K, Yoshida Y, Woltjen K, Horie M, Makita N, Kimura T.

Disrupted CaV1.2 selectivity causes overlapping long QT and Brugada syndrome phenotypes in the CACNA1C-E1115K iPS cell model Heart Rhythm. 2022 Aug 23:S1547-5271(22)02316-5.

Tsujisaka Y, Hatani T, Okubo C, Ito R, Kimura A, Narita M, Chonabayashi K, Funakoshi S, Lucena-Cacace A, Toyoda T, Osafune K, Kimura T, Saito H, Yoshida Y

Purification of human iPSC-derived cells at large scale using microRNA switch and magnetic-activated cell sorting Stem Cell Reports, 2022 May 30;S2213-6711(22)00255-7.

Tanabe M, Hosokawa K, Nguyen MAT, Nakagawa N, Maruyama K, Tsuji N, Urushihara R, Espinoza L, Elbadry MI, Mohiuddin M, Katagiri T, Ono M, Fujiwara H, Chonabayashi K, Yoshida Y, Yamazaki H, Hirao A, Nakao S.

The GPI-anchored protein CD109 protects hematopoietic progenitor cells from undergoing erythroid differentiation induced by TGF-β. Leukemia., 2022 Mar;36(3):847-855.

Junghof J, Kogure Y, Yu T, Verdugo-Sivianes EM, Narita M, Lucena-Cacace A, Yoshida Y.

CDH18 is a fetal epicardial biomarker regulating differentiation towards vascular smooth muscle cells. NPJ Regen Med., 2022 Feb 2;7(1):14.

Fujita Y, Hirosawa M, Hayashi K, Hatani T, Yoshida Y, Yamamoto T, Saito H.

A versatile and robust cell purification system with an RNA-only circuit composed of microRNA-responsive ON and OFF switches. Sci Adv., 2022 Jan 7;8(1):eabj1793.

Funakoshi S, Yoshida Y.

Recent progress of iPSC technology in cardiac diseases. Arch Toxicol., 2021 Dec;95(12):3633-3650.

Yuki Morimoto, Kazuhisa Chonabayashi, Hiroshi Kawabata, Chikako Okubo, Makiko Yamasaki-Morita, Misato Nishikawa, Megumi Narita, Azusa Inagaki, Kayoko Nakanishi, Miki Nagao, Akifumi Takaori-Kondo, Yoshinori Yoshida

Azacitidine is a potential therapeutic drug for pyridoxine-refractory female X-linked sideroblastic anemia. Blood Adv., 2021 Nov 15;bloodadvances.2021005664.

Chikako Okubo, Megumi Narita, Azusa Inagaki, Misato Nishikawa, Akitsu Hotta, Shinya Yamanaka, Yoshinori Yoshida

Expression dynamics of HAND1/2 in in vitro human cardiomyocyte differentiation Stem Cell Reports, 2021 Jul 8;S2213-6711(21)00322-2.

Kenji Miki, Kohei Deguchi, Misato Nakanishi-Koakutsu, Antonio Lucena-Cacace, Shigeru Kondo, Yuya Fujiwara, Takeshi Hatani, Masako Sasaki, Yuki Naka, Chikako Okubo, Megumi Narita, Ikue Takei, Stephanie C Napier, Tsukasa Sugo, Sachiko Imaichi, Taku Monjo, Tatsuya Ando, Norihisa Tamura, Kenichi Imahashi, Tomoyuki Nishimoto, Yoshinori Yoshida.

ERRγ enhances cardiac maturation with T-tubule formation in human iPSC-derived cardiomyocytes. Nat Commun., 2021 Jun 21;12(1):3596.

Mizumaki H, Hosomichi K, Hosokawa K, Yoroidaka T, Imi T, Zaimoku Y, Katagiri T, Anh Thi Nguyen M, Cao Tran D, Ibrahim Yousef Elbadry M, Chonabayashi K, Yoshida Y, Takamatsu H, Ozawa T, Azuma F, Kishi H, Fujii Y, Ogawa S, Tajima A, Nakao S.

A frequent nonsense mutation in exon 1 across certain HLA-A and -B alleles in leukocytes of patients with acquired aplastic anemia. Haematologica., 2021 Jun 1;106(6):1581-1590.

Nalbandian M, Zhao M, Sasaki-Honda M, Jonouchi T, Lucena-Cacace A, Mizusawa T, Yasuda M, Yoshida Y, Hotta A, Sakurai H.

Characterization of hiPSC-Derived Muscle Progenitors Reveals Distinctive Markers for Myogenic Cell Purification Toward Cell Therapy. Stem Cell Reports., 2021 Apr 13;16(4):883-898.

Karagiannis P, Yoshida Y.

Making Cardiomyocytes from Pluripotent Stem Cells. Methods Mol Biol., 2021;2320:3-7.

Miki K, Saito H, Yoshida Y.

Isolation of Cardiomyocytes Derived from Human Pluripotent Stem Cells using miRNA switches. Methods Mol Biol., 2021;2320:35-51.

Takaki T, Yoshida Y.

Application of FluoVolt membrane potential dye for induced pluripotent stem cell-derived cardiac single cells and monolayers differentiated via embryoid bodies. Methods Mol Biol., 2021;2320:101-110.

Nakanishi-Koakutsu M, Takaki T, Miki K, Yoshida Y.

Characterization of ventricular and atrial cardiomyocyte subtypes from human induced pluripotent stem cells. Methods Mol Biol., 2021;2320:135-149.

Fujiwara Y, Deguchi K, Miki K, Nishimoto T, Yoshida Y.

A method for contraction force measurements of hiPSC-derived engineered cardiac tissues. Methods Mol Biol., 2021;2320:171-180.

Okubo C, Narita M, Yamamoto T, Yoshida Y.

RNA-sequencing analysis of differentially expressed genes in human iPSC-derived cardiomyocytes. Methods Mol Biol., 2021;2320:193-217.

Lucena-Cacace A, Yoshida Y.

Analysis of Transcriptional Profiling of Chamber-specific Human Cardiac Myocytes Derived from Pluripotent Stem Cells. Methods Mol Biol., 2021;2320:219-232.

Hatani T, Yoshida Y.

Transplantation of Human Induced Pluripotent Stem Cell-derived Cardiomyocytes in a Mouse Myocardial Infarction Model. Methods Mol Biol., 2021;2320:285-293.

Ito E, Miyagawa S, Yoshida Y, Sawa Y.

Efficient Method to Dissociate Induced Pluripotent Stem Cell-Derived Cardiomyocyte Aggregates into Single Cells. Methods Mol Biol., 2021;2320:29-33.

Ono K, Shizuta S, Yamamoto E, Saito N, Ozasa N, Kato T, Kato E, Horie T, Tazaki J, Shiomi H, Watanabe S, Watanabe H, Yamashita Y, Yoshikawa Y, Kinoshita H, Makiyama T, Yoshida Y, Ashida N, Nakagawa Y, Nakashima Y, Baba O, Kohjitani H, Kimura M, Inazumi H, Yoshizawa T, Komasa A, Kimura T.

Overview of the 84th Annual Scientific Meeting of the Japanese Circulation Society 
- Change Practice!
Circ J., 85(3):323-329 (2021)

Fukushima H, Yoshioka M, Kawatou M, López-Dávila V, Takeda M, Kanda Y, Sekino Y, Yoshida Y, Yamashita JK.

Specific induction and long-term maintenance of high purity ventricular cardiomyocytes from human induced pluripotent stem cells. PLoS One., 15(11):e0241287 (2020)

Okamoto R, Goto I, Nishimura Y, Kobayashi I, Hashizume R, Yoshida Y, Ito R, Kobayashi Y, Nishikawa M, Ali Y, Saito S, Tanaka T, Sawa Y, Ito M, Dohi K.

Gap junction protein beta 4 plays an important role in cardiac function in humans, rodents, and zebrafish. PLoS One., 15(10):e0240129 (2020)

Hirose S, Makiyama T, Melgari D, Yamamoto Y, Wuriyanghai Y, Yokoi F, Nishiuchi S, Harita T, Hayano M, Kohjitani H, Gao J, Kashiwa A, Nishikawa M, Wu J, Yoshimoto J, Chonabayashi K, Ohno S, Yoshida Y, Horie M, Kimura T.

Propranolol Attenuates Late Sodium Current in a Long QT Syndrome Type 3-Human Induced Pluripotent Stem Cell Model. Front Cell Dev Biol., 8:761 (2020)

Kuwabara Y, Tsuji S, Nishiga M, Izuhara M, Ito S, Nagao K, Horie T, Watanabe S, Koyama S, Kiryu H, Nakashima Y, Baba O, Nakao T, Nishino T, Sowa N, Miyasaka Y, Hatani T, Ide Y, Nakazeki F, Kimura M, Yoshida Y, Inada T, Kimura T.

Lionheart LincRNA alleviates cardiac systolic dysfunction under pressure overload. Commun Biol., 3(1):434 (2020)

Nguyen MAT, Hosokawa K, Yoroidaka T, Maruyama H, Espinoza JL, Elbadry MI, Mohiuddin M, Tanabe M, Katagiri T, Nakagawa N, Chonabayashi K, Yoshida Y, Arima N, Kashiwase K, Saji H, Ogawa S, Nakao S.

Resistance of KIR Ligand-Missing Leukocytes to NK Cells In Vivo in Patients with Acquired Aplastic Anemia. Immunohorizons., 4(7):430-441 (2020)

Chonabayashi K, Yoshida Y, Kitawaki T, Nannya Y, Nakamura M, Oshima S, Hishizawa M, Yamashita K, Ogawa S, Takaori-Kondo A.

Acute myeloid leukemia with a cryptic NUP98/PRRX2 rearrangement developing after low-dose methotrexate therapy for rheumatoid arthritis. Ann Hematol. 2019 Nov 14. doi: 10.1007/s00277-019-03838-0. [Epub ahead of print]

Wu JC, Garg P, Yoshida Y, Yamanaka S, Gepstein L, Hulot JS, Knollmann BC, Schwartz PJ.

Towards Precision Medicine With Human iPSCs for Cardiac Channelopathies. Circ Res. 2019 Aug 30;125(6):653-658. doi: 10.1161/CIRCRESAHA.119.315209. Epub 2019 Aug 29

Xu H, Wang B, Ono M, Kagita A, Fujii K, Sasakawa N, Ueda T, Gee P, Nishikawa M, Nomura M, Kitaoka F, Takahashi T, Okita K, Yoshida Y, Kaneko S, Hotta A.

Targeted Disruption of HLA Genes via CRISPR-Cas9 Generates iPSCs with Enhanced Immune Compatibility. Cell Stem Cell. 2019 Apr 4;24(4):566-578.e7. doi: 10.1016/j.stem.2019.02.005.

Elbadry MI, Mizumaki H, Hosokawa K, Espinoza JL, Nakagawa N, Chonabayashi K, Yoshida Y, Katagiri T, Hosomichi K, Zaimoku Y, Imi T, Nguyen MAT, Fujii Y, Tajima A, Ogawa S, Takenaka K, Akashi K, Nakao S.

Escape hematopoiesis by HLA-B5401-lacking hematopoietic stem progenitor cells in men with acquired aplastic anemia. Haematologica. 2019 Mar 19. pii: haematol.2018.210856. doi: 10.3324/haematol.2018.210856.

Takaki T, Inagaki A, Chonabayashi K, Inoue K, Miki K, Ohno S, Makiyama T, Horie M, Yoshida Y*
* Corresponding author

Optical recording of action potentials in human induced pluripotent stem cell-derived cardiac single cells and monolayers generated from long QT syndrome type 1 patient Stem Cells Int. 2019 Mar 6;2019;7532657. doi: 10.1155/2019/7532657.

Karagiannis P, Takahashi K, Saito M, Yoshida Y, Okita K, Watanabe A, Inoue H, Yamashita J, Todani M, Nakagawa M, Osawa M, Yashiro Y, Yamanaka S, Osafune K

Induced Pluripotent Stem Cells and Their Use in Human Models of Disease and Development Physiol Rev. 2019 Jan 1;99(1):79-114. doi: 10.1152/physrev.00039.2017.

Hatani T, Funakoshi S, Deerinck TJ, Bushong EA, Kimura T, Takeshima H, Ellisman MH, Hoshijima M, Yoshida Y*.
* Corresponding author

Nano-structural analysis of engrafted human induced pluripotent stem cell-derived cardiomyocytes in mouse hearts using a genetic-probe APEX2. Biochem Biophys Res Commun. 2018 Nov 10;505(4):1251-1256.

Wuriyanghai Y, Makiyama T*, Sasaki K, Kamakura T, Yamamoto Y, Hayano M, Harita T, Nishiuchi S,
Chen J, Kohjitani H, Hirose S, Yokoi F, Gao J, Chonabayashi K, Watanabe K, Ohno S, Yoshida Y*, Kimura T,
Horie M
* Corresponding author

Complex aberrant splicing in the induced pluripotent stem cell-derived cardiomyocytes from a patient with long-QT syndrome carrying KCNQ1-A344Aspl mutation. Heart rhythm. 2018 Oct;15(10):1566-1574.

Hatani T, Miki K, Yoshida Y*
* Corresponding author

Induction of Human Induced Pluripotent Stem Cells to Cardiomyocytes Using Embryoid Bodies Methods Mol Biol. 2018;1816:79-92.

Espinoza JL, Elbadry MI, Chonabayashi K, Yoshida Y, Katagiri T, Harada K, Nakagawa N, Zaimoku Y, Imi T, Hassanein HA, Khalifa A Noreldin A, Takenaka K, Akashi K, Hamana H, Kishi H, Akatsuka Y, Nakao S.

Hematopoiesis by iPSC-derived hematopoietic stem cells of aplastic anemia that escape cytotoxic T-cell attack. Blood Adv. 2018 Feb 27;2(4):390-400.

Takeda M, Kanki Y, Masumoto H, Funakoshi S, Hatani T, Fukushima H, Izumi-Taguchi A, Matsui Y, Shimamura T, Yoshida Y, Yamashita JK.

Identification of Cardiomyocyte-Fated Progenitors from Human-Induced Pluripotent Stem Cells Marked with CD82. Cell Rep. 2018 Jan 9;22(2):546-556.

Hayano M, Makiyama T, Kamakura T, Watanabe H, Sasaki K, Funakoshi S, Wuriyanghai Y, Nishiuchi S, Harita T, Yamamoto Y, Kohjitani H, Hirose S, Yokoi F, Chen J, Baba O, Horie T, Chonabayashi K, Ohno S, Toyoda F, Yoshida Y, Ono K, Horie M, Kimura T.

The Development of a Patient-Derived Induced Pluripotent Stem Cell Model for the Investigation of SCN5A-D1275N-Related Cardiac Sodium Channelopathy. Circ J. 2017 Nov 24;81(12):1783-1791.

Kawamura M, Miyagawa S, Fukushima S, Saito A, Miki K, Funakoshi S, Yoshida Y, Yamanaka S, Shimizu T, Okano T, Daimon T, Toda T, Sawa Y.

Enhanced Therapeutic Effects of Human iPS Cell Derived-Cardiomyocyte by Combined Cell-Sheets with Omental Flap Technique in Porcine Ischemic Cardiomyopathy Model. Sci Rep.. 2017 Aug 18;7(1):8824.

Yoshida Y, Yamanaka S.

Induced Pluripotent Stem Cells Ten Years Later: For Cardiac Applications. Circ Res. 2017 Jun 9;120(12):1958-1968.

Kuang Y, Miki K, Parr CJ, Hayashi K, Takei I, Li J, Iwasaki M, Nakagawa M, Yoshida Y, Saito H.

Efficient and Selective Removal of Human Pluripotent Stem Cells via Ecto-Alkaline Phosphatase-Mediated Aggregation of Synthetic Peptides. Cell Chemical Biology. 2017 Jun 22;24(6):685-694.e4.

Kuang Y, Miki K, Parr CJ, Hayashi K, Takei I, Li J, Iwasaki M, Nakagawa M, Yoshida Y, Saito H.

Efficient and Selective Removal of Human Pluripotent Stem Cells via Ecto-Alkaline Phosphatase-Mediated Aggregation of Synthetic Peptides. Cell Chemical Biology. 2017 Jun 22;24(6):685-694.e4

Nakanishi H, Miki K, Komatsu KR, Umeda M, Mochizuki M, Inagaki A, Yoshida Y, Saito H.

Monitoring and visualizing microRNA dynamics during live cell differentiation using microRNA-responsive non-viral reporter vectors. Biomaterials. 2017 Jun;128:121-135.

Yamamoto Y, Makiyama T, Harita T, Sasaki K, Wuriyanghai Y, Hayano M, Nishiuchi S, Kohjitani H, Hirose S, Chen J, Yokoi F, Ishikawa T, Ohno S, Chonabayashi K, Motomura H, Yoshida Y, Horie M, Makita N, Kimura T.

Allele-specific ablation rescues electrophysiological abnormalities in a human iPS cell model of long-QT syndrome with a CALM2 mutation. Hum Mol Genet. 2017 May 1;26(9):1670-1677.

Ueki J, Nakamori M, Nakamura M, Nishikawa M, Yoshida Y, Tanaka A, Morizane A, Kamon M, Araki T, Takahashi MP, Watanabe A, Inagaki N, Sakurai M.

Myotonic dystrophy type 1 patient-derived iPSCs for the investigation of CTG repeat instability. Sci Rep. 2017 Feb 13;7:42522.

Sasaki K, Makiyama T, Yoshida Y, Wuriyanghai Y, Kamakura T, Nishiuchi S, Hayano M, Harita T, Yamamoto Y, Kohjitani H, Hirose S, Chen J, Itoh H, Kawamura M, Ohno S, Takeuchi A, Matsuoka S, Miura M, Sumitomo N, Horie M, Yamanaka S, Kimura T.

Patient-specific Human Induced Pluripotent Stem Cell Model Assessed with Electrical Pacing Validates S107 as a Potential Therapeutic Agent for Catecholaminergic Polymorphic Ventricular Tachycardia. PLoS One. 2016 Oct 20;11(10):e0164795

Parr CJ, Katayama S, Miki K, Kuang Y, Yoshida Y, Morizane A, Takahashi J, Yamanaka S, Saito H.

MicroRNA-302 switch to identify and eliminate undifferentiated human pluripotent stem cells. Sci Rep. 2016 Sep 9;6:32532.

Nishizawa M, Chonabayashi K, Nomura M, Tanaka A, Nakamura M, Inagaki A, Nishikawa M, Takei I, Oishi A, Tanabe K, Ohnuki M, Yokota H, Koyanagi-Aoi M, Okita K, Watanabe A, Takaori-Kondo A, Yamanaka S, Yoshida Y.

Epigenetic variation between human induced pluripotent stem cell lines is an indicator of differentiation capacity. Cell Stem Cell. 2016 Sep 1;19(3):341-54.

Oceguera-Yanez F, Kim SI, Matsumoto T, Tan GW, Xiang L, Hatani T, Kondo T, Ikeya M, Yoshida Y, Inoue H, Woltjen K.

Engineering the AAVS1 locus for consistent and scalable transgene expression in human iPSCs and their differentiated derivatives. Methods. 2016 May 15;101:43-55.

Kawamura T, Miyagawa S, Fukushima S, Maeda A, Kashiyama N, Kawamura A, Miki K, Okita K, Yoshida Y, Shiina T, Ogasawara K, Miyagawa S, Toda K, Okuyama H, Sawa Y.

Cardiomyocytes Derived from MHC-Homozygous Induced Pluripotent Stem Cells Exhibit Reduced Allogeneic Immunogenicity in MHC-Matched Non-human Primates. Stem Cell Reports. 2016 Mar 8;6(3):312-20

Morita Y, Andersen P, Hotta A, Tsukahara Y, Sasagawa N, Hayashida N, Koga C, Nishikawa M, Saga Y, Evans SM, Koshiba-Takeuchi K, Nishinakamura R, Yoshida Y, Kwon C, Takeuchi JK.

Sall1 transiently marks undifferentiated heart precursors and regulates their fate. J Mol Cell Cardiol. 2016 Mar;92:158-62

Yoshida Y, Yamanaka S.

Understanding Intracellular Signaling Advances Cardiac Reprogramming Technology Toward Clinical Applications. Circ Res. 2016 Feb 5;118(3):377-8.

Funakoshi S, Miki K, Takaki T, Okubo C, Hatani T, Chonabayashi K, Nishikawa M, Takei I, Oishi A, Narita M, Hoshijima M, Kimura T, Yamanaka S, Yoshida Y.

Enhanced engraftment, proliferation, and therapeutic potential in heart using optimized human iPSC-derived cardiomyocytes. Sci Rep. 2016 Jan 8;6:19111.

Miki K, Endo K, Takahashi S, Funakoshi S, Takei I, Katayama S, Toyoda T, Kotaka M, Takaki T, Umeda M, Okubo C, Nishikawa M, Oishi A, Narita M, Miyashita I, Asano K, Hayashi K, Osafune K, Yamanaka S, Saito H, Yoshida Y.

Efficient detection and purification of cell populations using synthetic microRNA switches.Cell Stem Cell. 2015 Jun 4;16(6):699-711

Tokunaga K, Saitoh N, Goldberg I, Sakamoto C, Yasuda Y, Yoshida Y, Yamanaka S, Nakao M.

Computational image analysis of colony and nuclear morphology to evaluate human induced pluripotent stem cells.Sci Rep. 2014 Nov 11;4:6996.

Nakagawa M, Taniguchi Y, Senda S, Takizawa N, Ichisaka T, Asano K, Morizane A, Doi D, Takahashi J, Nishizawa M, Yoshida Y, Toyoda T, Osafune K, Sekiguchi K, Yamanaka S.

A novel efficient feeder-free culture system for the derivation of human induced pluripotent stem cells.Sci Rep. 2014 Jan 8;4:3594.

Miki K, Yoshida Y, Yamanaka S.

Making Steady Progress on Direct Cardiac Reprogramming Toward Clinical Application.Circ Res. 2013 Jun 21;113(1):13-5.

Kamakura T, Makiyama T, Sasaki K, Yoshida Y, Wuriyanghai Y, Chen J, Hattori T, Ohno S, Kita T, Horie M, Yamanaka S, Kimura T.

Ultrastructural Maturation of Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes in a Long-Term Culture.Circ J. 2013 Apr 25;77(5):1307-14.

Yoshida Y, Yamanaka S.

An emerging strategy of gene therapy for cardiac disease.Circ Res. 2012 Oct 12;111(9):1108-10.

Yoshida Y, Yamanaka S.

Labor pains of new technology: direct cardiac reprogramming.Circ Res. 2012 Jun 22;111(1):3-4.

Yoshida Y, Yamanaka S.

iPS cells : A source of cardiac regeneration.J Mol Cell Cardiol. 2011 Feb;50(2):327-32.

Yoshida Y, Yamanaka S

Induced pluripotent stem cells for disease modeling and stem cell-based regeneration.Circulation. 2010 Jul 6;122(1):80-87.

Yoshida, Y., Takahashi, K., Okita, K., Ichisaka, T., and Yamanaka, S.

Hypoxia enhances the generation of induced pluripotent stem cells.Cell Stem Cell. 2009 5, 237-241.

Nakashima Y, Ono K, Yoshida Y, Kojima Y, Kita T, Tanaka M, Kimura T.

The search for Nkx2-5-regulated genes using purified embryonic stem cell-derived cardiomyocytes with Nkx2-5 gene targeting.Biochem Biophys Res Commun. 2009 Dec 18;390(3):821-826.

Kojima Y, Ono K, Inoue K, Takagi Y, Kikuta K, Nishimura M, Yoshida Y, Nakashima Y, Matsumae H, Furukawa Y, Mikuni N, Nobuyoshi M, Kimura T, Kita T, Tanaka M.

Progranulin expression in advanced human atherosclerotic plaque.Atherosclerosis. 2009 Sep;206(1):102-8.

Matsumae H, Yoshida Y, Ono K, Togi K, Inoue K, Furukawa Y, Nakashima Y, Kojima Y, Nobuyoshi M, Kita T, Tanaka M.

CCN1 knockdown suppresses neointimal hyperplasia in a rat artery balloon injury model.Arterioscler Thromb Vasc Biol. 2008 Jun;28(6):1077-83.

Yoshida Y, Togi K, Matsumae H, Nakashima Y, Kojima Y, Yamamoto H, Ono K, Nakamura T, Kita T, Tanaka M.

CCN1 protects cardiomyocytes from oxidative stress via beta1 integrin-Akt pathway.Biochem Biophys Res Commun. 2007 Apr 13; 355(3):611-8.

Kawamoto T, Togi K, Yamauchi R, Yoshida Y, Nakashima Y, Kita T, Tanaka M.

Endothelin-1 activates Homer 1alpha expression via mitogen-activated protein kinase in cardiac myocytes.Int J Mol Med. 2006 Jul;18(1):193-6.

Togi K, Yoshida Y, Matsumae H, Nakashima Y, Kita T, Tanaka M.

Essential role of Hand2 in interventricular septum formation and trabeculation during cardiac development.Biochem Biophys Res Commun. 2006 Apr 28; 343 (1):144-51.

Togi K, Kawamoto T, Yamauchi R, Yoshida Y, Kita T, Tanaka M.

Role of Hand1/eHAND in the dorso-ventral patterning and interventricular septum formation in the embryonic heart.Mol Cell Biol. 2004 Jun; 24(11):4627-35.
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